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M9470014.TXT
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1994-07-02
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Document 0014
DOCN M9470014
TI Crohn's ileitis in a patient with longstanding HIV infection.
DT 9409
AU Bernstein BB; Gelb A; Tabanda-Lichauco R; Division of Gastroenterology,
Beth Israel Medical Center, New; York, N.Y.
SO Am J Gastroenterol. 1994 Jun;89(6):937-9. Unique Identifier : AIDSLINE
MED/94256472
AB The differential diagnosis of diarrhea in patients infected with HIV is
broad, and includes a variety of bacterial, viral, and parasitic
pathogens, as well as malignancies including lymphoma and Kaposi's
sarcoma. Idiopathic non-specific inflammatory bowel disease rarely
occurs in association with HIV infection. A recent case report described
a patient with longstanding Crohn's disease who experienced remission of
his bowel disease upon infection with HIV (6). The authors inferred that
the remission was secondary to a depressed CD4 (T helper) lymphocyte
count. We report the first case of Crohn's ileitis developing in a
patient with established HIV infection, depressed CD4 lymphocyte count,
and no prior history of inflammatory bowel disease. This case raises
questions about the role of CD4 cells in the pathogenesis of Crohn's
disease.
DE Acquired Immunodeficiency Syndrome/*COMPLICATIONS/IMMUNOLOGY Case
Report Crohn Disease/*COMPLICATIONS/IMMUNOLOGY/PATHOLOGY Human
Ileum/PATHOLOGY Leukocyte Count Male Middle Age T4
Lymphocytes/IMMUNOLOGY JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).